To evaluate the efficacy of daily use of a CIALIS (Cialis, Tadalafil, and Vardenafil) in the treatment of erectile dysfunction.
We conducted a double-blind, randomized, placebo-controlled, double-dummy crossover study to compare the efficacy of daily CIALIS and tadalafil in the treatment of erectile dysfunction.
The study was conducted at a total of 3.8–5.8 weeks of treatment (average duration of 2.9 weeks) and 3.2–4.5 weeks of the control group. In the placebo group, the average duration of sexual intercourse at each time point was 5.5 (range 1–13) weeks. In the tadalafil group, the average duration of sexual intercourse at each time point was 2.9 (range 1.3–4.7) weeks. The mean duration of sexual intercourse at baseline was significantly less in the tadalafil group than in the placebo group (mean difference: -.02, 95% CI: -.13, -.08). The treatment effect was maintained at 4 weeks in most patients, with a significantly higher effect in the tadalafil group. The efficacy was maintained in only 25% of the patients in the tadalafil group and in only 30% in the placebo group. In patients treated with tadalafil, at least half of the patients achieved the desired effect, with a significantly lower incidence of adverse events in the tadalafil group.
Daily CIALIS, which is a selective phosphodiesterase-5 inhibitor, significantly improves erectile function in patients with erectile dysfunction. The effects are maintained for longer than 4 weeks and the safety profile for treatment of erectile dysfunction is not clearly defined. These results suggest that daily CIALIS may be a viable alternative for the treatment of erectile dysfunction.
Citation:Chen H, Guo Y, Liu H, Chen J, and Li Y, editors-in-Chief: Effects of daily CIALIS in the treatment of erectile dysfunction. PLoS ONE 10(5): e1065863. https://doi.org/10.1371/journal.pone.00361003
Editor:Ling Hao, The Chinese Academy of Medical Sciences, China
Received:February 23, 2019;Accepted:May 31, 2019;Published:June 12, 2019
Copyright:© 2019 Chen et al. This is an open-access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding:This work was supported by the National Natural Science Foundation of China (81277139 and 81200719) and the National Institutes of Health (Gimating grant Gimating Bioscription and Biopharmaceuticals Program and National Basic Research Program of China (2012BAA011501). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests:The authors have declared that no competing interests exist.
Erectile dysfunction (ED) is a common problem in the general population [], and is a major concern in many developed countries [,]. It is estimated that between 10% and 30% of the population are affected by ED []. The prevalence of ED is higher in men [,] and its prevalence in the general population is increasing [], and ED is associated with several physical, psychological, and social factors [–]. In order to effectively manage this condition and maintain sexual health, several therapeutic options exist that may be effective in the treatment of ED.
Daily CIALIS (CIALIS, Tadalafil, and Vardenafil) is one of the first oral phosphodiesterase-5 inhibitors developed for the treatment of erectile dysfunction (ED) []. It is the first oral phosphodiesterase-5 inhibitor of this class []. It is available in tablet form and is indicated for the treatment of ED in the treatment of erectile dysfunction.
In the current study, the effect of daily CIALIS was assessed in patients with erectile dysfunction (ED) compared with those who took a placebo (no medication).
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Q: My doctor has been prescribed tadalafil for my erectile dysfunction. I have had the same condition for a year now, and I’m not sure if it’s the medicine, or if it’s something I have to take for it.
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It may be due to your age or due to other factors, such as a previous heart attack or stroke. You can take tadalafil if you’re over 60, and your doctor will determine if you have other health conditions. You should also speak to your doctor about all the medicines you take. You may need to stop taking tadalafil if you develop new or worsening symptoms of erectile dysfunction.
Q: My girlfriend was recently diagnosed with a painful erectile dysfunction. I have had the same problem for two years. I am now 50.
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Q: I have been taking tadalafil for erectile dysfunction for about a year now. My doctor has told me that I need to see a specialist for erectile dysfunction. He said that I have an underlying condition that has been left untreated. He said that I should see a specialist for help. I was prescribed tadalafil for erectile dysfunction. Is there anything I need to do to get the right dosage of tadalafil?
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Q: I’m a 60-year-old male with erectile dysfunction and a history of a chronic heart problem. I’m currently taking Cialis. I’m looking forward to getting a prescription for tadalafil. Any advice?
A: Take tadalafil exactly as your doctor has told you. Tadalafil can be taken with or without food. Taking tadalafil with a heavy meal may make it more difficult to get an erection, but you should not take more than one dose within 24 hours. You should only take tadalafil with a fatty meal, and avoid taking it with a high-fat meal.
Q: I was prescribed tadalafil for erectile dysfunction. I was worried that it might cause side effects, and was worried that my erectile function might not be improved. I was told that it’s safe to take tadalafil to treat ED.
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Q: I’m 45 years old and have high blood pressure. I have been taking tadalafil for ED for about two years. My blood pressure is currently 130/70 mmHg, and I am wondering if it’s possible that my blood pressure could get higher when I was taking tadalafil.
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Cialis (Tadalafil) is a popular medication used to treat erectile dysfunction (ED). It is available in various dosages, including 5mg, 10mg, 20mg, and 40mg.
Cialis 5mg is a medication that is commonly prescribed for the treatment of erectile dysfunction (ED). It works by increasing blood flow to the penis, allowing for a firm and lasting erection.
Cialis (Tadalafil) is a medication that is specifically designed for men who have erectile dysfunction. It is not suitable for women who are trying to conceive or who are pregnant.
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Cialis (Tadalafil) is a popular medication for treating erectile dysfunction in men. It is available in different dosages, including 10mg, 20mg, and 40mg. It is important to note that the recommended dosage and usage frequency may vary depending on individual health conditions and the severity of ED symptoms.
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Cialis 10mg is a medication that is commonly prescribed for the treatment of erectile dysfunction (ED) in men.
It is available in different dosages, including 40mg, 50mg, and 100mg.
Cialis 10mg is a medication that is commonly prescribed for the treatment of erectile dysfunction (ED).
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